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Continuous integrated antibody precipitation with two‐stage tangential flow microfiltration enables constant mass flow

Continuous precipitation is a new unit operation for the continuous capture of antibodies. The capture step is based on continuous precipitation with PEG6000 and Zn(++) in a tubular reactor integrated with a two‐stage continuous tangential flow filtration unit. The precipitate cannot be separated wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biotechnol Bioeng
Hauptverfasser: Burgstaller, Daniel, Jungbauer, Alois, Satzer, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667901/
https://ncbi.nlm.nih.gov/pubmed/30636284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26922
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