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Continuous integrated antibody precipitation with two‐stage tangential flow microfiltration enables constant mass flow
Continuous precipitation is a new unit operation for the continuous capture of antibodies. The capture step is based on continuous precipitation with PEG6000 and Zn(++) in a tubular reactor integrated with a two‐stage continuous tangential flow filtration unit. The precipitate cannot be separated wi...
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| Veröffentlicht in: | Biotechnol Bioeng |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6667901/ https://ncbi.nlm.nih.gov/pubmed/30636284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26922 |
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