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Continuous capture of recombinant antibodies by ZnCl(2) precipitation without polyethylene glycol

The capture of recombinant antibodies from cell culture broth is the first critical step of downstream processing. We were able to develop a precipitation‐based method for the capture and purification of monoclonal antibodies based on divalent cations, namely ZnCl(2). Traditional precipitation proce...

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Detalhes bibliográficos
Publicado no:Eng Life Sci
Main Authors: Dutra, Gregory, Komuczki, Daniel, Jungbauer, Alois, Satzer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336134/
https://ncbi.nlm.nih.gov/pubmed/32647505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.201900160
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