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Continuous capture of recombinant antibodies by ZnCl(2) precipitation without polyethylene glycol

The capture of recombinant antibodies from cell culture broth is the first critical step of downstream processing. We were able to develop a precipitation‐based method for the capture and purification of monoclonal antibodies based on divalent cations, namely ZnCl(2). Traditional precipitation proce...

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Detalles Bibliográficos
Publicado en:Eng Life Sci
Main Authors: Dutra, Gregory, Komuczki, Daniel, Jungbauer, Alois, Satzer, Peter
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336134/
https://ncbi.nlm.nih.gov/pubmed/32647505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.201900160
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