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Continuous separation of protein loaded nanoparticles by simulated moving bed chromatography

For scale up and efficient production of protein loaded nanoparticles continuous separation by size exclusion chromatography in simulated moving bed (SMB) mode helps do reduce unbound protein concentration and increase yields for perfectly covered particles. Silica nanoparticles were loaded with an...

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Detalles Bibliográficos
Main Authors: Satzer, Peter, Wellhoefer, Martin, Jungbauer, Alois
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048465/
https://ncbi.nlm.nih.gov/pubmed/24866563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2014.04.093
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