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Continuous separation of protein loaded nanoparticles by simulated moving bed chromatography

For scale up and efficient production of protein loaded nanoparticles continuous separation by size exclusion chromatography in simulated moving bed (SMB) mode helps do reduce unbound protein concentration and increase yields for perfectly covered particles. Silica nanoparticles were loaded with an...

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Hlavní autoři: Satzer, Peter, Wellhoefer, Martin, Jungbauer, Alois
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048465/
https://ncbi.nlm.nih.gov/pubmed/24866563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2014.04.093
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