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Continuous separation of protein loaded nanoparticles by simulated moving bed chromatography

For scale up and efficient production of protein loaded nanoparticles continuous separation by size exclusion chromatography in simulated moving bed (SMB) mode helps do reduce unbound protein concentration and increase yields for perfectly covered particles. Silica nanoparticles were loaded with an...

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Bibliografske podrobnosti
Main Authors: Satzer, Peter, Wellhoefer, Martin, Jungbauer, Alois
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048465/
https://ncbi.nlm.nih.gov/pubmed/24866563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2014.04.093
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