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Interleukin-35 Induces Regulatory B Cells that Suppress CNS Autoimmune Disease

Interleukin 10-producing regulatory B-cells (Breg-cells) suppress autoimmune diseases while aberrant elevation of Breg-cells prevents sterilizing immunity, promotes carcinogenesis and cancer metastasis by converting resting CD4(+) T-cells to regulatory T-cells (Tregs). It is therefore of interest to...

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Detalhes bibliográficos
Main Authors: Wang, Ren-Xi, Yu, Cheng-Rong, Dambuza, Ivy M., Mahdi, Rashid M., Dolinska, Monika, Sergeey, Yuri V., Wingfield, Paul T., Kim, Sung-Hye, Egwuagu, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048323/
https://ncbi.nlm.nih.gov/pubmed/24743305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3554
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