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Interleukin-35 Induces Regulatory B Cells that Suppress CNS Autoimmune Disease
Interleukin 10-producing regulatory B-cells (Breg-cells) suppress autoimmune diseases while aberrant elevation of Breg-cells prevents sterilizing immunity, promotes carcinogenesis and cancer metastasis by converting resting CD4(+) T-cells to regulatory T-cells (Tregs). It is therefore of interest to...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048323/ https://ncbi.nlm.nih.gov/pubmed/24743305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3554 |
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