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Nicotinamide Mononucleotide, an Intermediate of NAD(+) Synthesis, Protects the Heart from Ischemia and Reperfusion
Nicotinamide phosphoribosyltransferase (Nampt), the rate-limiting enzyme for nicotinamide adenine dinucleotide (NAD(+)) synthesis, and Sirt1, an NAD(+)-dependent histone deacetylase, protect the heart against ischemia/reperfusion (I/R). It remains unknown whether Nampt mediates the protective effect...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048236/ https://ncbi.nlm.nih.gov/pubmed/24905194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098972 |
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