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Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy

Intestinal epithelial cells (IECs) not only have a critical function in the absorption of nutrients, but also act as a physical barrier between our body and the outside world. Damage and death of the epithelial cells lead to the breakdown of this barrier function and inflammation due to access of th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grabinger, T, Luks, L, Kostadinova, F, Zimberlin, C, Medema, J P, Leist, M, Brunner, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047863/
https://ncbi.nlm.nih.gov/pubmed/24832600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.183
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