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Intestinal ex vivo organoid culture reveals altered programmed crypt stem cells in patients with celiac disease

The ex vivo generation of gastrointestinal organoids from crypt stem cells opens up the possibility of new research approaches investigating gastrointestinal diseases. We used this technology to study differences between healthy controls and patients with celiac disease (CD). We noticed distinct dis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dieterich, Walburga, Neurath, Markus F., Zopf, Yurdagül
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044285/
https://ncbi.nlm.nih.gov/pubmed/32103108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60521-5
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