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Endothelial PINK1 mediates the protective effects of NLRP3 deficiency during lethal oxidant injury
High levels of inspired oxygen, hyperoxia, are frequently used in patients with acute respiratory failure. Hyperoxia can exacerbate acute respiratory failure, which has high mortality and no specific therapies. We identified a novel roles for PINK1 (PTEN-induced putative kinase 1), a mitochondrial p...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047670/ https://ncbi.nlm.nih.gov/pubmed/24778451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400653 |
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