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An endothelial TLR4-VEGFR2 pathway mediates lung protection against oxidant-induced injury
TLR4 deficiency causes hypersusceptibility to oxidant-induced injury. We investigated the role of TLR4 in lung protection, using used bone marrow chimeras; cell-specific transgenic modeling; and lentiviral delivery in vivo to knock down or express TLR4 in various lung compartments; and lung-specific...
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| Pubblicato in: | FASEB J |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Federation of American Societies for Experimental Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4750407/ https://ncbi.nlm.nih.gov/pubmed/26655705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275024 |
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