Endothelial CD74 mediates macrophage migration inhibitory factor protection in hyperoxic lung injury

Exposure to hyperoxia results in acute lung injury. A pathogenic consequence of hyperoxia is endothelial injury. Macrophage migration inhibitory factor (MIF) has a cytoprotective effect on lung endothelial cells; however, the mechanism is uncertain. We postulate that the MIF receptor CD74 mediates t...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Sauler, Maor, Zhang, Yi, Min, Jin-Na, Leng, Lin, Shan, Peiying, Roberts, Scott, Jorgensen, William L., Bucala, Richard, Lee, Patty J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2015
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415022/
https://ncbi.nlm.nih.gov/pubmed/25609432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-260299
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