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Immunoproteomics Using Polyclonal Antibodies and Stable Isotope–labeled Affinity-purified Recombinant Proteins

The combination of immuno-based methods and mass spectrometry detection has great potential in the field of quantitative proteomics. Here, we describe a new method (immuno-SILAC) for the absolute quantification of proteins in complex samples based on polyclonal antibodies and stable isotope–labeled...

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Autors principals: Edfors, Fredrik, Boström, Tove, Forsström, Björn, Zeiler, Marlis, Johansson, Henrik, Lundberg, Emma, Hober, Sophia, Lehtiö, Janne, Mann, Matthias, Uhlen, Mathias
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047479/
https://ncbi.nlm.nih.gov/pubmed/24722731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.034140
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