Absolute Quantification of Apolipoproteins Following Treatment with Omega-3 Carboxylic Acids and Fenofibrate Using a High Precision Stable Isotope-labeled Recombinant Protein Fragments Based SRM Assay

Stable isotope-labeled standard (SIS) peptides are used as internal standards in targeted proteomics to provide robust protein quantification, which is required in clinical settings. However, SIS peptides are typically added post trypsin digestion and, as the digestion efficiency can vary significan...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Hober, Andreas, Edfors, Fredrik, Ryaboshapkina, Maria, Malmqvist, Jonas, Rosengren, Louise, Percy, Andrew J., Lind, Lars, Forsström, Björn, Uhlén, Mathias, Oscarsson, Jan, Miliotis, Tasso
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885709/
https://ncbi.nlm.nih.gov/pubmed/31591263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001765
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