Absolute Quantification of Apolipoproteins Following Treatment with Omega-3 Carboxylic Acids and Fenofibrate Using a High Precision Stable Isotope-labeled Recombinant Protein Fragments Based SRM Assay

Stable isotope-labeled standard (SIS) peptides are used as internal standards in targeted proteomics to provide robust protein quantification, which is required in clinical settings. However, SIS peptides are typically added post trypsin digestion and, as the digestion efficiency can vary significan...

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Détails bibliographiques
Publié dans:Mol Cell Proteomics
Auteurs principaux: Hober, Andreas, Edfors, Fredrik, Ryaboshapkina, Maria, Malmqvist, Jonas, Rosengren, Louise, Percy, Andrew J., Lind, Lars, Forsström, Björn, Uhlén, Mathias, Oscarsson, Jan, Miliotis, Tasso
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885709/
https://ncbi.nlm.nih.gov/pubmed/31591263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001765
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