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Dominant Negative Effects of Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL) Receptor 4 on TRAIL Receptor 1 Signaling by Formation of Heteromeric Complexes

The cytokine TNF-related apoptosis-inducing ligand (TRAIL) and its cell membrane receptors constitute an elaborate signaling system fulfilling important functions in immune regulation and tumor surveillance. Activation of the death receptors TRAILR1 and TRAILR2 can lead to apoptosis, whereas TRAILR3...

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Bibliografische gegevens
Hoofdauteurs: Neumann, Simon, Hasenauer, Jan, Pollak, Nadine, Scheurich, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047423/
https://ncbi.nlm.nih.gov/pubmed/24764293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559468
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