High-throughput Assays for Superoxide and Hydrogen Peroxide: DESIGN OF A SCREENING WORKFLOW TO IDENTIFY INHIBITORS OF NADPH OXIDASES

Recent progress characterizing the reaction mechanism(s) of fluorescent probes with reactive oxygen species has made it possible to rigorously analyze these reactive species in biological systems. We have developed rapid high throughput-compatible assays for monitoring cellular production of superox...

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Bibliografiske detaljer
Main Authors: Zielonka, Jacek, Cheng, Gang, Zielonka, Monika, Ganesh, Thota, Sun, Aiming, Joseph, Joy, Michalski, Radosław, O'Brien, William J., Lambeth, J. David, Kalyanaraman, Balaraman
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047388/
https://ncbi.nlm.nih.gov/pubmed/24764302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548693
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