High-throughput Assays for Superoxide and Hydrogen Peroxide: DESIGN OF A SCREENING WORKFLOW TO IDENTIFY INHIBITORS OF NADPH OXIDASES

Recent progress characterizing the reaction mechanism(s) of fluorescent probes with reactive oxygen species has made it possible to rigorously analyze these reactive species in biological systems. We have developed rapid high throughput-compatible assays for monitoring cellular production of superox...

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Detalhes bibliográficos
Main Authors: Zielonka, Jacek, Cheng, Gang, Zielonka, Monika, Ganesh, Thota, Sun, Aiming, Joseph, Joy, Michalski, Radosław, O'Brien, William J., Lambeth, J. David, Kalyanaraman, Balaraman
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047388/
https://ncbi.nlm.nih.gov/pubmed/24764302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548693
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