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Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation
Using high throughput screening-compatible assays for superoxide and hydrogen peroxide, we identified potential inhibitors of the NADPH oxidase (Nox2) isoform from a small library of bioactive compounds. By using multiple probes (hydroethidine, hydropropidine, Amplex Red, and coumarin boronate) with...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807286/ https://ncbi.nlm.nih.gov/pubmed/26839313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702787 |
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