Flavone-resistant Leishmania donovani Overexpresses LdMRP2 Transporter in the Parasite and Activates Host MRP2 on Macrophages to Circumvent the Flavone-mediated Cell Death

In parasites, ATP-binding cassette (ABC) transporters represent an important family of proteins related to drug resistance and other biological activities. Resistance of leishmanial parasites to therapeutic drugs continues to escalate in developing countries, and in many instances, it is due to over...

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Bibliographic Details
Main Authors: Chowdhury, Sayan, Mukhopadhyay, Rupkatha, Saha, Sourav, Mishra, Amartya, Sengupta, Souvik, Roy, Syamal, Majumder, Hemanta K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047385/
https://ncbi.nlm.nih.gov/pubmed/24706751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539742
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