Flavone-resistant Leishmania donovani Overexpresses LdMRP2 Transporter in the Parasite and Activates Host MRP2 on Macrophages to Circumvent the Flavone-mediated Cell Death

In parasites, ATP-binding cassette (ABC) transporters represent an important family of proteins related to drug resistance and other biological activities. Resistance of leishmanial parasites to therapeutic drugs continues to escalate in developing countries, and in many instances, it is due to over...

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Main Authors: Chowdhury, Sayan, Mukhopadhyay, Rupkatha, Saha, Sourav, Mishra, Amartya, Sengupta, Souvik, Roy, Syamal, Majumder, Hemanta K.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2014
נושאים:
Microbiology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047385/
https://ncbi.nlm.nih.gov/pubmed/24706751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539742
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