Indomethacin Treatment Prevents High Fat Diet-induced Obesity and Insulin Resistance but Not Glucose Intolerance in C57BL/6J Mice

Chronic low grade inflammation is closely linked to obesity-associated insulin resistance. To examine how administration of the anti-inflammatory compound indomethacin, a general cyclooxygenase inhibitor, affected obesity development and insulin sensitivity, we fed obesity-prone male C57BL/6J mice a...

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Detalhes bibliográficos
Main Authors: Fjære, Even, Aune, Ulrike L., Røen, Kristin, Keenan, Alison H., Ma, Tao, Borkowski, Kamil, Kristensen, David M., Novotny, Guy W., Mandrup-Poulsen, Thomas, Hudson, Brian D., Milligan, Graeme, Xi, Yannan, Newman, John W., Haj, Fawaz G., Liaset, Bjørn, Kristiansen, Karsten, Madsen, Lise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047378/
https://ncbi.nlm.nih.gov/pubmed/24742673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525220
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