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Inhibitors of signal peptide peptidase (SPP) affect HSV-1 infectivity in vitro and in vivo

Recently we have shown that the highly conserved herpes simplex virus glycoprotein K (gK) binds to signal peptide peptidase (SPP), also known as minor histocompatibility antigen H13. In this study we have demonstrated for the first time that inhibitors of SPP, such as L685,458, (Z-LL)(2) ketone, asp...

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書誌詳細
主要な著者: Allen, Sariah J., Mott, Kevin R., Ghiasi, Homayon
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047190/
https://ncbi.nlm.nih.gov/pubmed/24768597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.04.004
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