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Inhibitors of signal peptide peptidase (SPP) affect HSV-1 infectivity in vitro and in vivo
Recently we have shown that the highly conserved herpes simplex virus glycoprotein K (gK) binds to signal peptide peptidase (SPP), also known as minor histocompatibility antigen H13. In this study we have demonstrated for the first time that inhibitors of SPP, such as L685,458, (Z-LL)(2) ketone, asp...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047190/ https://ncbi.nlm.nih.gov/pubmed/24768597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.04.004 |
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