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Inhibitors of signal peptide peptidase (SPP) affect HSV-1 infectivity in vitro and in vivo

Recently we have shown that the highly conserved herpes simplex virus glycoprotein K (gK) binds to signal peptide peptidase (SPP), also known as minor histocompatibility antigen H13. In this study we have demonstrated for the first time that inhibitors of SPP, such as L685,458, (Z-LL)(2) ketone, asp...

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Dettagli Bibliografici
Autori principali: Allen, Sariah J., Mott, Kevin R., Ghiasi, Homayon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047190/
https://ncbi.nlm.nih.gov/pubmed/24768597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.04.004
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