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Involvement of STAT4 in IgG subtype switching and ocular HSV-1 replication in mice

PURPOSE: To assess the relative impact of elevated T-helper 2 (T(H)2)- and reduced T-Helper 1 (T(H)1)-dependent immune responses on ocular herpes simplex virus type 1 (HSV-1) infection. METHODS: Signal transducer and activator of transcription protein 4 knockout mice (BALB/c-STAT4(−/−)) and wild-typ...

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Detalhes bibliográficos
Main Authors: Allen, Sariah J., Mott, Kevin R., Ghiasi, Homayon
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810873/
https://ncbi.nlm.nih.gov/pubmed/20104254
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