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ChR2 Mutants at L132 and T159 with Improved Operational Light Sensitivity for Vision Restoration
The ectopic expression of microbial opsin-based optogenetic sensors, such as channelrhodopsin-2 (ChR2) in surviving inner retinal neurons, is a promising approach to restoring vision after retinal degeneration. However, a major limitation in using native ChR2 as a light sensor for vision restoration...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047080/ https://ncbi.nlm.nih.gov/pubmed/24901492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098924 |
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