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ChR2 Mutants at L132 and T159 with Improved Operational Light Sensitivity for Vision Restoration

The ectopic expression of microbial opsin-based optogenetic sensors, such as channelrhodopsin-2 (ChR2) in surviving inner retinal neurons, is a promising approach to restoring vision after retinal degeneration. However, a major limitation in using native ChR2 as a light sensor for vision restoration...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Pan, Zhuo-Hua, Ganjawala, Tushar H., Lu, Qi, Ivanova, Elena, Zhang, Zhifei
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047080/
https://ncbi.nlm.nih.gov/pubmed/24901492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098924
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