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Comparison of AAV-Mediated Optogenetic Vision Restoration between Retinal Ganglion Cell Expression and ON Bipolar Cell Targeting

The loss of photoreceptors in individuals with retinal degenerative diseases leads to partial or complete blindness. Optogenetic therapy is a promising approach for restoring vision to the blind. Multiple strategies have been employed by targeting genetically encoded light sensors, particularly chan...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Lu, Qi, Ganjawala, Tushar H., Krstevski, Andrea, Abrams, Gary W., Pan, Zhuo-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287188/
https://ncbi.nlm.nih.gov/pubmed/32548211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.05.009
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