Ectopic Expression of Multiple Microbial Rhodopsins Restores ON and OFF Light Responses in Retinas with Photoreceptor Degeneration

By expressing channelrhodopsin-2 (ChR2) in inner retinal neurons, previous studies have demonstrated restoration of ON responses in the retina after the death of rod and cone photoreceptors. In this study, we report that the expression of halorhodopsin (HaloR), a light-driven chloride pump, can effe...

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Bibliographic Details
Main Authors: Zhang, Yi, Ivanova, Elena, Bi, Anding, Pan, Zhuo-Hua
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774241/
https://ncbi.nlm.nih.gov/pubmed/19625509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0184-09.2009
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