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Clinical Light Exposure, Photoreceptor Degeneration, and AP-1 Activation: A Cell Death or Cell Survival Signal in the Rhodopsin Mutant Retina?

PURPOSE: The T4R RHO mutant dog retina shows retinal degeneration with exposures to light comparable to those used in clinical eye examinations of patients. To define the molecular mechanisms of the degeneration, AP-1 DNA-binding activity, composition, posttranslational modification of the protein c...

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Detalhes bibliográficos
Main Authors: Gu, Danian, Beltran, William A., Li, Zexiao, Acland, Gregory M., Aguirre, Gustavo D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377016/
https://ncbi.nlm.nih.gov/pubmed/17962438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0428
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