Oxidative Stress Decreases Functional Airway Mannose Binding Lectin in COPD

We have previously established that a defect in the ability of alveolar macrophages (AM) to phagocytose apoptotic cells (efferocytosis) and pathogens is a potential therapeutic target in COPD. We further showed that levels of mannose binding lectin (MBL; required for effective macrophage phagocytic...

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Detalhes bibliográficos
Main Authors: Tran, Hai B., Ahern, Jessica, Hodge, Greg, Holt, Phillip, Dean, Melinda M., Reynolds, Paul N., Hodge, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047017/
https://ncbi.nlm.nih.gov/pubmed/24901869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098571
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