A Protein-Conjugate Approach to Develop a Monoclonal Antibody-Based Antigen Detection Test for the Diagnosis of Human Brucellosis

Human brucellosis is most commonly diagnosed by serology based on agglutination of fixed Brucella abortus as antigen. Nucleic acid amplification techniques have not proven capable of reproducibly and sensitively demonstrating the presence of Brucella DNA in clinical specimens. We sought to optimize...

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Bibliografiska uppgifter
Huvudupphovsmän: Patra, Kailash P., Saito, Mayuko, Atluri, Vidya L., Rolán, Hortensia G., Young, Briana, Kerrinnes, Tobias, Smits, Henk, Ricaldi, Jessica N., Gotuzzo, Eduardo, Gilman, Robert H., Tsolis, Renee M., Vinetz, Joseph M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046965/
https://ncbi.nlm.nih.gov/pubmed/24901521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002926
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