Antigen-Specific Acquired Immunity in Human Brucellosis: Implications for Diagnosis, Prognosis, and Vaccine Development

Brucella spp., are Gram negative bacteria that cause disease by growing within monocyte/macrophage lineage cells. Clinical manifestations of brucellosis are immune mediated, not due to bacterial virulence factors. Acquired immunity to brucellosis has been studied through observations of naturally in...

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Autori principali: Cannella, Anthony P., Tsolis, Renee M., Liang, Li, Felgner, Philip L., Saito, Mayuko, Sette, Alessandro, Gotuzzo, Eduardo, Vinetz, Joseph M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2012
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417515/
https://ncbi.nlm.nih.gov/pubmed/22919593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2012.00001
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