A Protein-Conjugate Approach to Develop a Monoclonal Antibody-Based Antigen Detection Test for the Diagnosis of Human Brucellosis

Human brucellosis is most commonly diagnosed by serology based on agglutination of fixed Brucella abortus as antigen. Nucleic acid amplification techniques have not proven capable of reproducibly and sensitively demonstrating the presence of Brucella DNA in clinical specimens. We sought to optimize...

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Detalhes bibliográficos
Main Authors: Patra, Kailash P., Saito, Mayuko, Atluri, Vidya L., Rolán, Hortensia G., Young, Briana, Kerrinnes, Tobias, Smits, Henk, Ricaldi, Jessica N., Gotuzzo, Eduardo, Gilman, Robert H., Tsolis, Renee M., Vinetz, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046965/
https://ncbi.nlm.nih.gov/pubmed/24901521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002926
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