A Protein-Conjugate Approach to Develop a Monoclonal Antibody-Based Antigen Detection Test for the Diagnosis of Human Brucellosis

Human brucellosis is most commonly diagnosed by serology based on agglutination of fixed Brucella abortus as antigen. Nucleic acid amplification techniques have not proven capable of reproducibly and sensitively demonstrating the presence of Brucella DNA in clinical specimens. We sought to optimize...

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Main Authors: Patra, Kailash P., Saito, Mayuko, Atluri, Vidya L., Rolán, Hortensia G., Young, Briana, Kerrinnes, Tobias, Smits, Henk, Ricaldi, Jessica N., Gotuzzo, Eduardo, Gilman, Robert H., Tsolis, Renee M., Vinetz, Joseph M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046965/
https://ncbi.nlm.nih.gov/pubmed/24901521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002926
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