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Site-specific contributions to the pH dependence of protein stability
Understanding protein stability is a significant challenge requiring characterization of interactions within both folded and unfolded states. Of these, electrostatic interactions influence ionization equilibria of acidic and basic groups and diversify their pK(a) values. The pH dependence of the the...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC404695/ https://ncbi.nlm.nih.gov/pubmed/12671071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0736600100 |
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