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Site-specific contributions to the pH dependence of protein stability

Understanding protein stability is a significant challenge requiring characterization of interactions within both folded and unfolded states. Of these, electrostatic interactions influence ionization equilibria of acidic and basic groups and diversify their pK(a) values. The pH dependence of the the...

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Detalhes bibliográficos
Main Authors: Tollinger, Martin, Crowhurst, Karin A., Kay, Lewis E., Forman-Kay, Julie D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC404695/
https://ncbi.nlm.nih.gov/pubmed/12671071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0736600100
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