TPL2 kinase regulates the inflammatory milieu of the myeloma niche

Targeted modulation of microenvironmental regulatory pathways may be essential to control myeloma and other genetically/clonally heterogeneous cancers. Here we report that human myeloma–associated monocytes/macrophages (MAM), but not myeloma plasma cells, constitute the predominant source of interle...

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Detalhes bibliográficos
Main Authors: Hope, Chelsea, Ollar, Samuel J., Heninger, Erika, Hebron, Ellen, Jensen, Jeffrey L., Kim, Jaehyup, Maroulakou, Ioanna, Miyamoto, Shigeki, Leith, Catherine, Yang, David T., Callander, Natalie, Hematti, Peiman, Chesi, Marta, Bergsagel, P. Leif, Asimakopoulos, Fotis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046426/
https://ncbi.nlm.nih.gov/pubmed/24723682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554071
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