RhoA mediates defective stem cell function and heterotopic ossification in dystrophic muscle of mice

Heterotopic ossification (HO) and fatty infiltration (FI) often occur in diseased skeletal muscle and have been previously described in various animal models of Duchenne muscular dystrophy (DMD); however, the pathological mechanisms remain largely unknown. Dystrophin-deficient mdx mice and dystrophi...

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Bibliographic Details
Main Authors: Mu, Xiaodong, Usas, Arvydas, Tang, Ying, Lu, Aiping, Wang, Bing, Weiss, Kurt, Huard, Johnny
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2013
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046169/
https://ncbi.nlm.nih.gov/pubmed/23704088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-233460
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