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RhoA mediates defective stem cell function and heterotopic ossification in dystrophic muscle of mice

Heterotopic ossification (HO) and fatty infiltration (FI) often occur in diseased skeletal muscle and have been previously described in various animal models of Duchenne muscular dystrophy (DMD); however, the pathological mechanisms remain largely unknown. Dystrophin-deficient mdx mice and dystrophi...

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Autori principali: Mu, Xiaodong, Usas, Arvydas, Tang, Ying, Lu, Aiping, Wang, Bing, Weiss, Kurt, Huard, Johnny
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046169/
https://ncbi.nlm.nih.gov/pubmed/23704088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-233460
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