Bax Inhibitor-1-Mediated Inhibition of Mitochondrial Ca(2+) Intake Regulates Mitochondrial Permeability Transition Pore Opening and Cell Death

A recently studied endoplasmic reticulum (ER) stress regulator, Bax inhibitor-1 (BI-1) plays a regulatory role in mitochondrial Ca(2+) levels. In this study, we identified ER-resident and mitochondria-associated ER membrane (MAM)-resident populations of BI-1. ER stress increased mitochondrial Ca(2+)...

Full description

Saved in:
Bibliographic Details
Main Authors: Lee, Geum-Hwa, Lee, Hwa-Young, Li, Bo, Kim, Hyung-Ryong, Chae, Han-Jung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046133/
https://ncbi.nlm.nih.gov/pubmed/24899098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05194
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items