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Bax Inhibitor-1-Mediated Inhibition of Mitochondrial Ca(2+) Intake Regulates Mitochondrial Permeability Transition Pore Opening and Cell Death
A recently studied endoplasmic reticulum (ER) stress regulator, Bax inhibitor-1 (BI-1) plays a regulatory role in mitochondrial Ca(2+) levels. In this study, we identified ER-resident and mitochondria-associated ER membrane (MAM)-resident populations of BI-1. ER stress increased mitochondrial Ca(2+)...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046133/ https://ncbi.nlm.nih.gov/pubmed/24899098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05194 |
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