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Mitochondrial Ca(2+) and Regulation of the Permeability Transition Pore

The mitochondrial permeability transition pore was originally described in the 1970’s as a Ca(2+) activated pore and has since been attributed to the pathogenesis of many diseases. Here we evaluate how each of the current models of the pore complex fit to what is known about how Ca(2+) regulates the...

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Pubblicato in:J Bioenerg Biomembr
Autori principali: Hurst, Stephen, Hoek, Jan, Sheu, Shey-Shing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393273/
https://ncbi.nlm.nih.gov/pubmed/27497945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-016-9672-x
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