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The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore

Excessive production of mitochondrial reactive oxygen species (mROS) is strongly associated with mitochondrial and cellular oxidative damage, aging, and degenerative diseases. However, mROS also induces pathways of protection of mitochondria that slow aging, inhibit cell death, and increase lifespan...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Rottenberg, Hagai, Hoek, Jan B.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595682/
https://ncbi.nlm.nih.gov/pubmed/28758328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12650
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