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The Mitochondrial Permeability Transition: Nexus of Aging, Disease and Longevity
The activity of the mitochondrial permeability transition pore, mPTP, a highly regulated multi-component mega-channel, is enhanced in aging and in aging-driven degenerative diseases. mPTP activity accelerates aging by releasing large amounts of cell-damaging reactive oxygen species, Ca(2+) and NAD(+...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cells |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
MDPI
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7825081/ https://ncbi.nlm.nih.gov/pubmed/33418876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010079 |
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