טוען...

Functional avidity and IL-2/perforin production is linked to the emergence of mutations within HLA-B*5701-restricted epitopes and HIV-1 disease progression

Viral escape from HIV-1-specific CD8(+) T cells has been demonstrated in numerous studies previously. However, the qualitative features driving the emergence of mutations within epitopes are still unclear. In this study, we aimed to distinguish whether specific functional characteristics of HLA-B*57...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Buggert, Marcus, Norström, Melissa M, Salemi, Marco, Hecht, Frederick M, Karlsson, Annika C
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046013/
https://ncbi.nlm.nih.gov/pubmed/24740510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302253
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