Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection

While the relationship of protective human leukocyte antigen (HLA) class I alleles and HIV progression is well defined, the interaction of HLA-mediated protection and CD8 T-cell exhaustion is less well characterized. To gain insight into the influence of HLA-B*57:01 on the deterioration of CD8 T-cel...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Scharf, Lydia, Tauriainen, Johanna, Buggert, Marcus, Hartogensis, Wendy, Nolan, David J., Deeks, Steven G., Salemi, Marco, Hecht, Frederick M., Karlsson, Annika C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343205/
https://ncbi.nlm.nih.gov/pubmed/32350076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02128-19
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