Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes

BACKGROUND: The HLA-B*35-Px allele has been associated with rapid disease progression in HIV-1 infection, in contrast to the HLA-B*35-Py allele. METHODOLOGY/PRINCIPAL FINDINGS: Immune responses to two HLA-B*35 restricted HIV-1 specific CTL epitopes and their variants were followed longitudinally dur...

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Main Authors: Willberg, Christian B., Garrison, Keith E., Jones, R. Brad, Meiklejohn, Duncan J., Spotts, Gerald, Liegler, Teri J., Ostrowski, Mario A., Karlsson, Annika C., Hecht, Frederick M., Nixon, Douglas F.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858076/
https://ncbi.nlm.nih.gov/pubmed/20422053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010249
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