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Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression

Rare inherited cardiovascular diseases are frequently caused by mutations in genes that are essential for the formation and/or function of the cardiovasculature. Hereditary Haemorrhagic Telangiectasia is a familial disease of this type. The majority of patients carry mutations in either Endoglin (EN...

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Bibliografski detalji
Glavni autori: Tual-Chalot, Simon, Mahmoud, Marwa, Allinson, Kathleen R., Redgrave, Rachael E., Zhai, Zhenhua, Oh, S. Paul, Fruttiger, Marcus, Arthur, Helen M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045906/
https://ncbi.nlm.nih.gov/pubmed/24896812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098646
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