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Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression

Rare inherited cardiovascular diseases are frequently caused by mutations in genes that are essential for the formation and/or function of the cardiovasculature. Hereditary Haemorrhagic Telangiectasia is a familial disease of this type. The majority of patients carry mutations in either Endoglin (EN...

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Détails bibliographiques
Auteurs principaux: Tual-Chalot, Simon, Mahmoud, Marwa, Allinson, Kathleen R., Redgrave, Rachael E., Zhai, Zhenhua, Oh, S. Paul, Fruttiger, Marcus, Arthur, Helen M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045906/
https://ncbi.nlm.nih.gov/pubmed/24896812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098646
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