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Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression

Rare inherited cardiovascular diseases are frequently caused by mutations in genes that are essential for the formation and/or function of the cardiovasculature. Hereditary Haemorrhagic Telangiectasia is a familial disease of this type. The majority of patients carry mutations in either Endoglin (EN...

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Hlavní autoři: Tual-Chalot, Simon, Mahmoud, Marwa, Allinson, Kathleen R., Redgrave, Rachael E., Zhai, Zhenhua, Oh, S. Paul, Fruttiger, Marcus, Arthur, Helen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045906/
https://ncbi.nlm.nih.gov/pubmed/24896812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098646
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